Carolina at Chapel Hill for testing the antituberculostatic activity of 3-fluoroisonicotinic acid hydrazide; these tests show low activity, 160 /xg./ml. being necessary to inhibit growth in vitro (7). EXPERIMENTAL S-and 5-Nitro-9-hydroxy-i-picoline (Ilia, Illb). Following the method of Hawkins and Roe (3) for an isomeric compound, a 50-g. sample of 2-amino-4-picoline was converted to
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