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Hoffmann-La Roche, during the conduct of the study, and editorial support funded by the sponsor and provided by an independent medical writer under the guidance of the authors. Cappuzzo has been a consultant/advisor for AstraZeneca, Bristol-Myers Squibb, Merck Sharp & Dohme, Pfizer, Roche, and Takeda; received a grant and nonfinancial support from F. Hoffmann-La Roche during the conduct of the study; and received editorial support funded by the sponsor and provided by an independent medical writer under the guidance of the authors. Rodríguez-Abreu has participated in speakers' bureaus for AstraZeneca, Bristol-Myers Squibb, Merck Sharp & Dohme, Pfizer, and Roche; received a grant and nonfinancial support from F. Hoffmann-La Roche during the conduct of the study; and received editorial support funded by the sponsor and provided by an independent medical writer under the guidance of the authors. Hussein has participated in speakers' bureaus for Bristol-Myers Squibb, Incyte, and Pfizer. Soo has received grants from AstraZeneca and Boehringer-Ingelheim and personal fees from AstraZeneca,