The human hand is one of the most important instruments for the psychomotricity of being human and any chronic problem such as Rheumatoid Arthritis (RA) implies the need for a scheduled and serial rehabilitation from the medical point of view that controls and verifies its effectiveness over time. Rheumatoid arthritis is one of the chronic diseases with the greatest social impact today that mainly affects older people. RA is considered to affect a person's activities and quality of life, especially in older adults, where the affectations are mostly significant and require attention. Through computeraided controlled rehabilitation, the thesis presents, on the one hand, an investigation on exoskeletons for chronic rehabilitation and on the other, the creation and validation of an exoskeletal device for the hand called ARTH-AID System that will serve to improve the rehabilitation of the arthritic hand that suffers a progressive muscular atrophy.The system created represents a significant help through the integration of certain factors such as: ergonomics, functionality and design. It has been designed and tested with end users taking into account the mechanical and functional factors in the progressive loss of manual hand mobility in older people with chronic RA. The rehabilitation system includes as a fundamental part an exoskeleton in the hand that evaluates the dynamics and progress of a user's rehabilitation, generating confidence and satisfaction in the patient during the sessions and improving the interaction with the physiotherapist. The methodology and design of an exoskeleton glove for the rehabilitation of chronic RA patients has been developed and evaluated considering aspects related to Design Thinking (DT) and User-Centered Design (DCU). Likewise, in the creation and technological implementation of the system, computer and electronic technologies oriented to the management of management system and control of programmed movements through an integrated electronic board have been taken into account, finally Computer Aided Design (DAO) applications and Rapid Prototyping (PR) tools have been used for the generation of computer simulations and articulated physical parts implemented in the glove.The validation of the system was carried out at the Santa Catalina Labouré Nursing Home, in Quito, Ecuador, first with a group of experts composed of the physiotherapists who work in the center and that allowed to analyze its feasibility as an integrated system in the current rehabilitation process and later with a group of potential users or patients controlled therapeutically from the center, that allowed to validate the functionality of the device, verify its effectiveness and evaluate the level of satisfaction within the user experience.