Glasses with SiO 2 -CaO-ZnO-B 2 O 3 -K 2 O-Al 2 O 3 composition modified by addition of titania (3, 5, 12 and 20% w) have been prepared by sol-gel method. The obtained gels were aged, dried and fired at 600ºC/1h in order to stabilise the glass. The resulting fired powders were characterised by UV-Vis-NIR spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray diffraction (XRD). Their photocatalytic capacity on the degradation of orange II dye has been studied. The XRD and TEM results indicate that system is amorphous with a nanostructured microstructure. From UV-Vis-NIR results the band gap calculated is around 3.5 eV for all samples. Photoactivity of powders depends on amount of titania in glass composition and the surface area of prepared samples. The sample with highest surface area and lowest addition of titania (3% w. sample) shows similar activity than commercial anatase used as reference.