Yang-Mills Theories in Algebraic Non-Covariant Gauges Downloaded from www.worldscientific.com by 44.224.250.200 on 12/13/20. Re-use and distribution is strictly not permitted, except for Open Access articles.

The possibility of a small modification of spinor Quantum Electro-Dynamics is reconsidered, in which Lorentz and CPT non-covariant kinetic terms for photons and fermions are present. The corresponding free field theory is carefully discussed. The finite one-loop parity-odd induced effective action is unambiguously calculated using the physical cutoff method, which manifestly encodes the maximal residual symmetry group allowed by the presence of the Lorentz and CPT breaking axial-vector. This very same induced effective action, which is different from those ones so far quoted in the Literature, is also re-derived by means of the dimensional regularization, provided the maximal residual symmetry is maintained in the enlarged D-dimensional space-time. As a consequence, it turns out that the requirement of keeping the maximal residual symmetry at the quantum level just corresponds to the physical renormalization prescription which naturally fixes the one-loop parity-odd induced effective action.

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A novel series of β-lactam derivatives that was designed and synthesized to target RGD-binding and leukocyte integrins is reported. The compound library was evaluated by investigating the effects on integrin-mediated cell adhesion and cell signaling in cell lines expressing αβ, αβ, αβ, αβ, αβ, αβ, and αβ integrins. SAR analysis of the new series of azetidinones enabled the recognition of structural elements associated with integrin selectivity. We obtained selective and potent agonists that could induce cell adhesion and promote cell signaling mediated by αβ, αβ, αβ, or αβ integrin, and antagonists for the integrins αβ and αβ as well as αβ and αβ, preventing the effects elicited by the respective endogenous agonists.