Treatment with azelaic acid 20 % cream significantly improves acne severity and disease-related QoL in adult women.

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Nicergoline (NE)--a cerebral vasodilator with nicotinic acid esterified in its molecule--and Antagonic-Stress (AS) composition--a neurometabolic nootropic, also containing nicotinic acid but with fast and prolonged release--were evaluated in senile dementia of Alzheimer's type (SDAT), mild to moderate intensity (DSM-IV Options Book, 1991 and ICD-10, 1990 criteria). A double-blind, randomized, comparative, and parallel clinical trial was performed on 62 old people divided into 2 groups and exclusively treated with NE or AS. Psychogeriatric evaluations (Sandoz Clinical Assessment-Geriatric scale, Self-Assessment Scale-Geriatric and their subscales) and psychometric tests (digit symbol of WAIS, Wechsler Memory Scale, and Wechsler Adult Intelligence Scale-WAIS) were made before and after 3 months of treatment. Prolonged and large dose treatments with NE and AS significantly decreased the psychogeriatric scores, diminished the deterioration index, and improved cognitive performances (ANOVA). Therapeutical effects of AS were significantly higher than those of NE (ANCOVA). The better actions of AS in senile dementia and for improving cognitive function and behavior are discussed in connection with its multiple neurometabolic composition, the synergism of components, the antiischemic action of its antioxidants, its anti-free radical complementary action (deceleration of the aging rate, brain and erythrocyte lipofuscinolysis, complex antioxidative and scavenger formula), the multivitamin and multimineral supplementation and, finally, with the superiority of multitherapy vs. monotherapy.

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In this study we applied the sociometric research technique of the student class to identify the sociometric status of students characterized as victims of bullying. The sociometric position and the perception of the bullying victim status were tested by applying the sociometric test on a sample of 31 students in a humanities class (11th) of a high school in Brăila, Romania. The results of the self-esteem measuring instrument were also used by applying the Rosenberg technique. The results of the study showed that there was a visible difference between the rejected number 6 (Isp = 0.4), for which 2 votes and 14 rejections were expressed and the rejected number 2, chosen by 3 colleagues and rejected by 4 (Isp = -0.03). Also, the grouping of those with Isp = 0 in the category of the indi ff erent ones