Purpose Sporotrichosis is the most common subcutaneous mycosis in the world and it is presented usually in the lymphocutaneous form. When the eye is involved, it typically includes the conjunctival and periorbital tissues or even the intraocular tissues. Observations We present a case of a 13-year-old girl complaining about nodules in the left malar region and in both the outer nasal corner and the lower eyelid of the left eye, which had appeared one month earlier. Conclusions and significance: Sporotrichosis is a hyperendemic disease in Brazil and its diagnosis is based on clinical aspects, epidemiological history, and culture. Ophthalmologists and other professionals should be aware of this condition.

Melkersson-Rosenthal syndrome (MRS) is a rare condition without any known etiology. It is characterized by the triad facial paralysis, facial swelling, and the development of folds and furrows at the tongue (fissured tongue). This study aims to report a case of a 59-year-old patient complaining about asymmetric eyelid swelling that had started two years before, associated with pain and redness on her right eye, without repercussions on her visual acuity. The patient underwent a skin biopsy of the right eye’s lower eyelid, which was compatible with the monosymptomatic form of MRS. Consequently, five injections of triamcinolone were performed for the period of one year, with gradual and satisfactory improvement. One year after the end of the treatment, the patient returned with recurrence of the swelling, and therapy with triamcinolone associated with oral steroids was started. However, due to the lack of improvement, Tacrolimus ointment 0.03% was initiated. The patient evolved with an important and significant reduction of the eyelid edema, still being followed at the Hospital Federal dos Servidores do Estado do Rio de Janeiro.

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