Seven cases of aseptic meningitis were diagnosed in an intensive care nursery within the same period of time that 12 infants and older children with aseptic meningitis were admitted to the pediatric services of two hospitals in the same city. In two of the seven neonatal cases, and in seven of the 12 cases in older children coxsackievirus B5 was isolated from either spinal fluid or rectal swab specimens. Routine isolation precautions were insufficient to contain the spread of infection within the nursery. A comparison of the spinal fluid findings and clinical symptoms demonstrated a broad spectrum of severity in both neonates and older children. No neonates or young infants developed myocarditis. The possible sources of infection and the implications of nursery participation in a community epidemic are discussed.
\s=b\With the use of ethanol in hyperalimentation regimens and for the inhibition of premature labor, there is increased opportunity for exposure of the fetus to this potentially toxic substance. We reviewed the literature regarding the effects of ethanol on the fetus and neonate, and illustrate its potential toxicity by the report of a case of neonatal depression secondary to acute maternal ethanol ingestion.(Am J Dis Child 129: [1075][1076] 1975)
Various p a r t i a l trisomy syndromes have been described s i n c e the advent of t h e chromosome banding techniques. However, a documented case of p a r t i a l trisomy 7p has, a s yet, not been reported. We have recently detected t h i s aberration i n a four month o l d fanale i n f a n t who presented with t h e following anomal i e s : asymmetric cranium with widely patent a n t e r i o r fontanelle and metopic suture, deep widow's peak, hypertelorism, b i l a t e r a l choanal a t r e s i a , prominent nasal bone, low s e t , rotated e a r s , maxillary hypoplasia, high arched palate, micrognathia, arachnodactyly with contractures of t h e interphalangeal j o i n t s , cong e n i t a l l y dislocated h i p , and v e r t i c a l t a l u s . Ihe p a t i e n t ' s banded karyotype revealed a 46,XX,5p+ ccmplement. With G, Q, and R banding, a 46,XY.t (517) (plSipl5) karyotype was found i n t h e father. Studies on the mother were normal. Iherefore, it is
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