The Sanskrit term Ayurveda has translated knowledge of life. It is one of the world's oldest healing systems that originated in eastern culture and it includes numerous medical concepts and it’s a hypothesis for treatment and prevention of disease. In ancient times near to 3000 years ago in India when there are no synthetic medicines was developed then people used Ayurvedic plants to get cures for different diseases. Ayurveda is based on a belief that health and wellness depend on a delicate balance of mind, body, and spirit. Ayurvedic herbs are key components of Ayurveda. COVID-19 is an infectious disease found in December 2019 and it has now become a pandemic. The COVID-19 infection is produced by virulent severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) virus although various antiviral drugs are available for controlling the infection but sometimes, they lack in supply for treating the worldwide population. So, it has become imperative to develop an effective medical strategy for the management of COVID-19 which has become a major threat to humanity. Herbs exhibit various biological activities so; they can effectively help with managing the pandemic. This review discussed some herbs which have the potential for the treatment of COVID-19.
Polycystic ovary disorder (PCOD) is hormonal disorder among reproductive-age women. Causing enlarged ovaries with small cysts on the outer edges in patients with PCOD, the secretion rate and metabolism of androgens and estrogens are disrupted. The pathophysiology of the syndrome is complex and there is no single defect from which it is known to result, it is hypothesized that insulin resistance is a key factor. With regards to the increasing prevalence of PCOD and associated mental and physical problemsas well as the effects of changes in sex hormones in development of this disease, our aim is to investigate the effects of synthetic drug and herbal drug in the serum levels of sex hormones and ovarian tissue. Several Pharmacological studies have described the use of various Ayurvedic medicinal plants and their constituents play the important role for the treatment of PCOD.Therefore, this drug can be partly effective in this syndrome via affecting the different hormones and serum levels of ovarian morphology, weight and representing an opportunity to investigate and discovery new bioactive products. This review discussed some synthetic and herbal drug which has the potential for the treatment of PCOD.
Spinal muscular atrophy (SMA) is the second leading genetic, autosomal recessive disorder with progressive weakness of skeletal and respiratory muscles, leading to progressive paralysis with muscular atrophy, significant disability. SMA predominantly affects on children and represents the most common cause of hereditary infant mortality. Spinal muscular atrophy caused by mutations in the survival motor neuron 1 (SMN1) gene and a consequentdecrease in the SMN protein leading to lower motor neuron degeneration. The clinical features of Spinal muscular atrophy are caused by specific degeneration of a-motor neurons in the spinal cord, leading to muscle weakness, atrophy and, in the majority of cases, premature death. Encouraging results from phase II and III clinical trials have raised hope that other therapeutic options will enter soon in clinical practice. The common genetic etiology and recent progress in pre-clinical models suggest that SMA is well-suited for the development of therapeutic regimens. This review covers the available data and the new challenges of SMA therapeutic strategies.
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