Background: A Burden of diabetes and hypertension is on rise in India. India, being a developing country, has unique problems regarding the treatment compliance which is a serious risk for morbidity and mortality. Hypertension is major risk factors for cardiovascular and cerebrovascular disease. Compliance is a primary determinant of the effectiveness of treatment because poor compliance attenuates optimum clinical benet and paves the way for complications. To assess the compliance to treatment Aim: of hypertension of diagnosed patients and study various factors affecting the compliance of treatment of hypertension. Cross sectional study conduc Materials And Methods: ted in the tertiary care hospital non communicable disease clinic. All the cases of hypertension diagnosed for more than 6 months were included. The data were collected over a period of two months (August -September 2021). All the study participants were interviewed using a semi- structured questionnaire after obtaining informed verbal consent. questionnaire was including details on demography, medical documentation, treatment details and factors assessing the, knowledge about hypertension and compliance towards the disease treatment. A t Results: otal 260 hypertensive participated in this study. According to Morisky8 scale of compliance of treatment of hypertension, 44.23% and 55.77% of participants were having moderate and low compliance, respectively. Males had lower compliance than females. Patients with comorbidities and on multiple medications, longer duration of treatment, senior citizens were factors related to non-compliance. In this study 67.3% of the respondents had comorbidities. Patients having hypertension with other comorbidities were poor compliant on treatment than who had not comorbidities. According to Morisky 8 Conclusion: scale compliance of treatment of hypertension, 44.23% and 55.77% of participants were having moderate and low compliance respectively. Males had lower compliance than females. Patients with comorbidities and on multiple medications, longer duration of treatment, senior citizens were factors related to non-compliance.