3‐Fluoro‐2‐arylimidazo[1,2‐a]pyridines were selectively synthesised in one‐pot from acetophenones and 2‐aminopyridines under mild conditions. The sequence of reactions involved bromination, condensation, and late‐stage fluorination. Two halogenating reagents play key roles in the process. We found that tetrabutylammonium tribromide and SelectfluorTM gave excellent yields of the desired products in the one‐pot sequential reaction.
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