BACKGROUNDWe are herewith reporting a case of acinic cell carcinoma arising in nasal cavity in a 52-year-old male patient. The diagnosis was confirmed by immunohistochemistry for DOG1, which is a novel marker for salivary acinic cell differentiation. Nasal cavity is a rare site for acinic cell carcinoma and pathologists and surgeons should include this entity also in the differential diagnosis of tumours of nasal cavity to avoid misdiagnosis.

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Atrial myxoma is the most common primary cardiac neoplasm. It is a tumor of adults, most often seen in women aged 20 to 60 years. Most commonly arise in isolated fashion (90%) but few (10%) can be associated with carney complex (myxoma syndrome) an autosomal dominant disease seen in younger age group. Left sided myxomas present signs of mitral stenosis or insufficiency and right sided tumors with dyspnea, syncope, distension of neck veins is seen. Two dimensional echocardiography, CT, MRI, gated radionuclide blood-pool scan, or cardiac catheterization can all visualize myxomas, but cannot differentiate between other pedunculated tumors or thrombi. It is important to rule out Carney complex because chances of recurrence are much higher than when compared to non syndromic myxomas. Hereby in this case report we discuss a large atrial myxoma in female who presented with breathlessness and chest pain.

Central giant cell granuloma is a reparative bony lesion characterised by abundant multinucleated giant cells within a sea of spindle shaped mesenchymal stromal cells. Giant cells are scattered throughout the fibrovascular connective tissue stroma containing hemorrhage. Its coexistence with parathyroid adenoma is very rare. Brown tumour is a close differential in this scenario. Herein we present the case of a central giant cell granuloma of maxilla and parathyroid adenoma diagnosed almost during the same time in a 58 years old male.