The topographical location and histological type of breast cancer in the city of Goiania followed the pattern of other countries. The main morphological types were not influenced by age. There was a large increase in initial cases.

Objective: to analyze the overall survival and prognostic factors of women with breast cancer in the city of Goiânia. Methods: this is a retrospective, cross-sectional, observational study that included women with malignant neoplasms of the breast identified by the Goiânia Population-based Cancer Registry. The variables studied were age at diagnosis, tumor size, staging, axillary lymph node involvement, tumor grade, disease extent, hormone receptors, and c-erb-B2 oncoprotein. We performed overall survival analyzes of five and ten years. Results: we included 2,273 patients in the study, with an overall survival of 72.1% in five years and 57.8% in ten years. In the multivariate analysis adjusted for tumor size, the factors that influenced the prognosis were axillary lymph nodes, histological grade, progesterone receptor, c erb B2, T staging and disease extension. Conclusion: overall survival in ten years is below that observed in other countries, and possibly reflects what happens with the majority of the Brazilian population. The prognostic factors found in this population follow the same international patterns.

RESUMO O presente estudo foi desenvolvido com o objetivo de avaliar o metabolismo do ferro por meio da determinação

Objetivou-se avaliar os efeitos do uso de rações com diferentes níveis de inclusão de água para suínos na fase de creche por meio de parâmetros de digestibilidade e de desempenho. Foram estabelecidos três tratamentos, correspondendo a (T1) ração basal seca e farelada, (T2) ração basal com a inclusão de água na proporção de 1:1 (1kg de água para 1kg de ração) e (T3) proporção de 2:1 (2 kg de água para 1 kg de ração). No experimento de digestibilidade foram utilizados 12 leitões machos castrados, com peso médio de 19,09 ± 2,88 kg. O delineamento experimental utilizado para o ensaio de metabolismo foi o inteiramente casualizado, com três tratamentos e quatro repetições. Na avaliação de desempenho foram utilizados 36 suínos mestiços de linhagem comercial, com peso inicial de 12,32 ± 1,4 kg, sendo 18 fêmeas e 18 machos castrados, em um delineamento experimental inteiramente casualizado, com três tratamentos e seis repetições, perfazendo 18 unidades experimentais, sendo cada repetição constituída por um macho castrado e uma fêmea. Rações com diferentes níveis de inclusão de água não influenciaram (P>0,05) (valor de P) o desempenho dos animais e o coeficiente de digestibilidade; entretanto, o coeficiente de metabolizabilidade da proteína bruta foi maior (P<0,05) para a relação 1:1 água/ração em relação ao grupo controle.PALAVRAS-CHAVE: consumo; conversão alimentar; crescimento; desempenho; digestibilidade; ração úmida.

The objective was to determine the digestible tryptophan requirements for male broilers in pre-starter and starter phases. Two experiments using 400 Cobb broilers were performed 200 males in the first experiment for the pre-starter phase (one to seven days old), and 200 males in the second experiment for the starter phase (eight to 21 days old). Chicks were housed in batter boxes made of galvanized steel as an experimental shed. The experiments were performed in a completely randomized design, with four treatments and five replicates, with ten birds each. In both experiments, the tryptophan requirement was determined using diets with different levels of digestible tryptophan. A tryptophan-deficient diet was formulated, as a basal diet, which was supplemented with increased levels of L-tryptophan in order to achieve the desirable digestible tryptophan levels. Treatments consisted of 0.209% (basal diet); 0.223%; 0.235% and 0.248% digestible tryptophan for the pre-starter phase (experiment 1) and 0.187% (basal diet); 0.200%, 0.211% and 0.223% digestible tryptophan for the starter phase (experiment 2). We evaluated feed intake, weight gain and feed conversion, as well as the metabolizability of feed nutrients. The performance and metabolic data were subjected to analysis of variance, and estimates of digestible tryptophan levels were made through polynomial regression models at 5% probability. There was no significant difference between the digestible tryptophan levels in the diet over performance and digestibility in both treatments. It is possible to conclude that the basal diet with 0.209% digestible tryptophan for the pre-starter phase and 0.187% for the starter phase, at a tryptophan: lysine ratio of 16%, as sufficient to meet the broilers requirements. Key words: Animal nutrition. Chickens. Digestible amino acid. Digestibility. Performance. ResumoObjetivou-se determinar as exigências de triptofano digestível para frangos de corte machos nas fases pré-inicial e inicial. Foram realizados dois experimentos utilizando 400 frangos de corte da linhagem Cobb, sendo o experimento 1 com 200 machos para a fase pré-inicial (um a sete dias de idade), e o 1 M.e em Ciência Animal, Escola de Medicina Veterinária e Zootecnia, EVZ, Universidade Federal de Goiás, UFG, Goiânia, GO,Brasil. E-mail: brunozootecnia22@hotmail.com 2 Profs., Pós-Graduação em Zootecnia, EVZ/UFG, Goiânia, GO, Brasil. E-mail: romaocnunes@hotmail.com; jhstring@uol.com. br; alegimenez09@hotmail.com; heloisamello@gmail.com 3 Discentes do Curso de Doutorado em Zootecnia, EVZ/UFG, Goiânia, GO, Brasil. E-mail: julyanamachado_zoo@hotmail.com; raianazoo@hotmail.com; mary_zoo@hotmail.com * Author for correspondence experimento 2 com 200 machos para a fase inicial (oito a 21 dias de idade), alojados em baterias, contendo gaiolas de arame galvanizado, em um galpão experimental. Os experimentos foram realizados em delineamento inteiramente casualizado, divididos em quatro tratamentos, com cinco repetições e dez aves por repetição, sendo que cada repetição com...