The pharmaceutically significant 2,3-dihydroquinolin-4-one scaffolds were constructed diastereoselectively and facilely via redox-neutral cascade Knoevengel condensation/[1,7]-hydride transfer/cyclization/transesterification in DCE from readily available methyl 2-aminobenzoacetate and diverse aldehydes, which features novel &...

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The pharmaceutically significant scaffolds of 2,3-dihydroquinolin-4-one and benzoazepine-5-one carrying privileged 3,3’-spirocyclic oxindole moiety were controllably constructed relying on cascade condensation/redox-neutral [1,6]/[1,7]-hydride transfer/cyclization in green alcoholic media from 2-aminoacetophenone and diverse...