The similarities and differences between toxic/nutritional and hereditary optic neuropathy and the pathophysiologic mechanisms that they have in common are described. This is based on data from the epidemic suffered in Cuba in 1992, which affected the optic nerves of many individuals and the experience of the authors in dealing with various toxic optic neuropathies, as well as Leber's hereditary optic neuropathy.

OCT is probably one of the most revolutionary technologies that has appeared in ophthalmology in recent years. We are still trying to understand and clarify the use of OCT in neuro-ophthalmology. In this article we share our experience using various OCT devices over the last ten years, as well as the experience of others as reported in the literature.

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