This study sought to formulate and evaluate herbal lipstick using Beta vulgaris and Lawsonia inermis as natural colorants. Lipsticks contribute to 60 per cent of the world's commonly used cosmetics to enhance appearance, emblem a woman's strength, power, and ambition and give the first impression. However, 75 per cent of available lipsticks are made up of synthetic excipients, including colorants that pose health hazards and safety concerns; hence need to use natural excipients that are safe and readily available. A moulding process successfully formulated the herbal lipstick. The formulated lipstick had uniform dark red colour, with a good force of application and spread ability. It had a melting point of 60 degrees Celcius and a breaking point of 55. The project was an experimental based study and analytical in nature. The area of study was in the Pharmacognosy lab from the initial steps of extraction. Formulation and evaluation of the lipstick samples were done in the Pharmaceutics laboratory. The study concluded that Herbal excipients are safe and readily available and hence should be exploited in the formulation of cosmetic products. This study recommends further evaluation of lipstick for safety and efficacy. In addition, the stability of the formulated lipstick under different storage conditions should be performed.
The research objective was to determine the physical stability and concentration of amoxicillin reconstituted oral suspension (125mg/5ml) stored under room temperature of 25°C and refrigeration temperature of 2-8°C days 1, 3, and 7. Three different brands of amoxicillin samples were used. Samples from the reconstituted amoxicillin suspension was assayed by HPLC to determine the concentration of the active and examined physically for taste, odour and colour change. The drug concentration for all three brands during the seven days ranged from 88.94 per cent - 102.17 per cent for refrigerated and 89.57-99.7 per cent for reconstituted amoxicillin at room temperature. The odour for days 1, 3 and 7 is fruity. The colour was pale yellow for days 1 and 3, while on day 7, it was creamy yellow. The taste was sweet on days 1 and 3, while on day 7, it was sweet/low bitter. The three brands maintained their potency and physical stability as required in the British pharmacopoeia. The reconstituted antibiotic suspensions must be stored at room temperature or in a refrigerator to maintain potency throughout their use. However, a good number of patients do not adhere to storage specifications resulting in the degradation of the product and subsequent loss of potency. The results for day one for all the drugs fall within the accepted range, drug K has its percent concentration the lowest, and microbiological studies should be done on this drug to ascertain microbial stability.
The aim of the study was to determine the side effects associated with the misuse of topical corticosteroids in Litein Town, Kericho County. A convenient random sample of 57 respondents was selected for the study. Self-developed structured questionnaire was used in data collection. In this study, figures were used to present data. The latest version of the SPSS data analysis tool was used to derive frequencies and percentages from the demographic information provided the use of corticosteroids and side effects associated with the use of corticosteroids. Common side effects related to the misuse of TCS include reduced immunity, change in skin pigmentation, thinning of skin, itching and abnormal drying. TCS are readily bought from community pharmacies for treatment and cosmetic purposes. Various brands are available in the market, with clozole cream as the most commonly known. The majority buy TCS for treatment purposes, while others for cosmetic purposes. Common side effects include drying, itching, change in pigmentation and dryness. This study recommends that necessary measures are to be put in place to improve the outcome of patients undergoing treatment for dermatological conditions using TCS through occasional monitoring of the patient. In addition, formulating scientists should work on formulating TCS with good anti-inflammatory effects and minimal adverse effects. This will ensure good compliance among patients.
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