A space-time analysis of American visceral leishmaniasis (AVL) in humans in 1 . Dogs are considered important reservoir hosts in urban areas as they carry the agent for long periods of time, favoring biologic vector-borne infections and, as a result, maintenance of protozoa 2,3 . In human begins, AVL is described as a serious disease and early diagnosis and treatment are vital to avoid fatalities 4,5 .In Brazil, AVL affects most parts of the national territory and represents an important public health issue, especially in fast-growing urban areas. Recent data shows that cases reported in this country make up 90% of all cases registered in Latin America 5 . In the State of São Paulo, canine visceral leishmaniasis occurs in 71 cities while the human form is present in 52 urban centers 6 .Despite the prevention and control measures implemented in the State of São Paulo, human and canine AVL are still spreading 6 . One of the most affected cities is Bauru, where 354 human cases were confirmed between 2003 (data collected up to April 2011 7 . Up to date, the space-time pattern of this disease in the City of São Paulo has not been evaluated, emphasizing the need for studies that address this question.ARTIGO ARTICLE

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In light of recent efforts in Brazil to increase B19 strain vaccine coverage of heifers, this study proposes a standardized methodology for the calculation of vaccination coverage among the Federal Units. To illustrate its use, the method was applied to data from the state of Mato Grosso to calculate vaccination coverage from 2006 to 2010. The results provide the best estimate based on data currently available in most states and can be easily adapted to situations in which the cattle registries use different age categories from those used in the state of Mato Grosso. Key words: Brucellosis. Bovine. Vaccination coverage. ResumoTendo em vista o grande esforço que o Brasil vem fazendo para aumentar a cobertura vacinal de bezerras com a amostra B19, propõe-se metodologia padronizada para o cálculo da cobertura vacinal das Unidades Federativas. Para exemplificar sua utilização, o método foi aplicado aos dados do estado do Mato Grosso para calcular a cobertura vacinal no período de 2006 a 2010. Os resultados obtidos forneceram a melhor estimativa possível a partir dos dados atualmente disponíveis na maioria dos estados e pode ser facilmente adaptado para situações nas quais o registro do efetivo bovino se utilize de categorias etárias com amplitude diferente das utilizadas no estado do Mato Grosso. Palavras-chave: Brucelose. Bovino. Cobertura vacinal.