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Dysgranulopoiesis is a condition in which granulocytic production is defective and is most often described in neoplastic conditions. However, it can also be frequently seen in non‐neoplastic conditions. Early suspicion and detection of these non‐neoplastic causes may prevent further invasive and expensive interventions. In this review, we take a look at the various causes of dysgranulopoiesis with an emphasis on non‐neoplastic etiologies, followed by a detailed outline of the laboratory approach for determining its many causes.

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