The present study is a retrospective analysis of allelic frequency of ABO and Rhesus (D) blood groups of donors attending the Deaprtment of Transfusion Medicine of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka. BIRDEM IS a 625 bed hospital, where patients and blood donors come from all parts of Bangladesh. A total of 1, 28,506 blood donors of both genders were included in the study over fourteen years from June 1995 to June 2009 for analysis. Blood group was determined by performing the both tube and slide method blood grouping method. The distribution of blood groups in our population was B>O>A>AB in Rh positive groups donors and O>B>A>AB among Rh negative donors. Blood group B was more common among the males (37.42%) while O was predominant among female donors (33.83 %). On the other hand, blood group O negative was predominant in both genders (36.88%). In this study, Hardy-Weinberg equilibrium law was used to calculate the allelic frequency for ABO/ Rh system. Homozygous allelic frequency for Rh negative population was only 0.0007. Although phenotypically B group was dominant and AB was rare in our population, but according to Hardy-Weinberg equilibrium law the estimated allelic frequency of A (0.3694) and O (0.3040) showed higher frequency than B type (0.2300) in Bangladeshi population in both homozygous and heterozygous state. So, with increasing population of Bangladesh, this changing trend in estimated blood group in ABO system may play an important role in our genetic pattern.Ibrahim Med. Coll. J. 2011; 5(2): 59-62

Aims: The aims of the study were to compare the safety and benefits of laparoscopic versus open appendicectomy.Methods: This cross-sectional study was done in BIRDEM General Hospital from June 2005 to December 2006.Seventy patients with acute appendicitis were included in this study, half underwent laparoscopic procedure and half open conventional procedure.We evaluated the length of hospitalization, postoperative morbidity (pain, wound infection, chest complication, paralytic ileus),cosmesis and return to normal activity among two methods of operations.Results: The duration of surgery in open group was 30 to 70 minutes with a mean duration of 47.57 minutes. In case of laparoscopic group the mean duration was 38.71 minutes with a range from 30 to 60 minutes. In open group 28 cases (80.0%) required opioid for satisfactory pain relief whereas in laparoscopic group only 9 (25.71%) cases required opioid. Gross infection with pus collection occurred in 2 (5.7%) cases in open appendicectomy (OA) group and none inlaparoscopic appendicectomy (LA) group. Post-operative hospital stay in open group ranged from 2 to 18 days with a mean of 6.74 days. For laparoscopic group the duration was 1 to 5 days with a mean of 2.31 days. Patients in open procedure returned to normal activity within 11-23 days with a mean of 15 days and in lap group the figures were 2-15 days and 6 days respectively. In open group 65.71% (n=23) were satisfied with the scar they had whereas 91.4% (n=32) were satisfied with their scar in lap group.Conclusion: The study indicates that the laparoscopic appendicectomy is feasible and safe for majority of patients with acute appendicitis.Birdem Med J 2015; 5(1) Supplement: 13-17

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