Background Our aims were to determine the usability and practicality of the endoscope-i system, a novel mobile attachment for aural endoscopy. This incorporated assessing the ease of use of the endoscope-i for different professionals, and ultimately improving the system by receiving constructive feedback. Objective Our objectives were to assess the ease of the endoscope-i system in conducting an aural examination and to assess its feasibility for integrating its use into clinical practice. We looked to assess its ease, effectiveness, and efficiency; to compare this to current practices with otoscopes; and to determine whether participants perceived the system to be able to produce an image of sufficient quality to make a clinical assessment. Finally, we wanted to assess the usefulness of the current training given for using the system, and we sought to gain feedback for the product from the differing specialists. Methods A formative usability study of the endoscope-i system was conducted with 5 health care professionals. Each session lasted 40 minutes and involved audio/video consent, a hands-on session, a private semistructured interview, and an option to discuss the device with a company representative. Results All participants found the endoscope-i system easy to use. The image quality was perceived to be greater than that achieved by current otoscopes. The ability to record images and view them retrospectively was also seen as a positive. Conclusions This study has not identified any significant issues relating to the design, functionality, or application of the endoscope-i. Participants perceived the system as superior to current options with a directly positive impact on their clinical practice.