Objectives:This study aimed to analyze the effects of propolis extract and propolis candies on Streptococcus sanguinis.Methods: Bacterial suspensions were exposed to propolis extract and propolis candies. For propolis extract, a minimum inhibitory concentration (MIC) was determined using a spectrophotometer, and a minimum bactericidal concentration (MBC) was determined using a standard plate count method. Samples were cultured in brain heart infusion agar, incubated for 24 hrs, and the bacterial colony units formed on the agar plates were manually counted.Results: Propolis extract inhibits the growth of S. sanguinis at MIC 5% and MBC 10%. The colonies of S. sanguinis decreased after exposure to propolis candies. Conclusions:Propolis extract and propolis candies are effective to inhibit the growth of S. sanguinis.