Specific haplotypes and SNPs in IL10 gene are associated with susceptibility to CP in Brazilian patients.

We concluded that the IL-6-174 polymorphism is associated with susceptibility to chronic periodontitis in the population studied.

These results show that a polymorphism in the promoter region of MMP-1 gene is associated with the severe chronic periodontitis phenotype in non-smokers.

TaqI and BsmI polymorphisms of the VDR gene are associated with clinical attachment loss due to periodontal disease in a Brazilian population. These findings suggest that VDR genotype might be a risk indicator for susceptibility to chronic periodontitis.

No abstract