To improve the bioactivity and oral bioavailability of myricetin, a microemulsion formulation was successfully developed, which consisted of Cremophor RH40 (12%), Tween 80 (6%), Transcutol HP (9%), WL 1349 (18%), and distilled water (55%). With lower content of surfactants and higher stability after dilution and storage for 6 months, the optimized myricetin microemulsion (MYR-ME) could dramatically enhance the solubility of myricetin 1225 times that in water. MYR-ME significantly increased antiproliferative activity against human cancer cell HepG2 without influence on normal cell LO2. It also notably improved the cellular antioxidative activity of myricetin. Furthermore, the oral bioavailability of myricetin was remarkably enhanced by MYR-ME in Sprague-Dawley rats after oral administration, which was 14.43-fold that with myricetin suspension. Therefore, the MYR-ME developed here could be used as a potential carrier for myricetin with substantially enhanced bioactivities and bioavailability and might promote myricetin's future utilization in functional foods and cosmetics.

Identifying the effects of urban sprawl on urban development is of strategic importance. This study takes 285 prefecture-level and above cities in China as research samples and empirically analyzes the heterogeneous impact of urban sprawl on economic development from 2009 to 2018. Results indicate the threshold effect of urban sprawl on economic development. That is, moderate urban sprawl has a significantly positive influence on economic development, whereas excessive urban sprawl has a significantly negative impact on economic development. The empirical analysis also identifies heterogeneities in the effects of urban sprawl on economic development. Compared with the sprawls of small- and medium-sized cities, those of large cities have a greater negative impact on economic development. Compared with the sprawls of cities dominated by the tertiary industry, those of cities dominated by the secondary industry have a greater negative impact on economic development. Findings of this study have important policy implications for scientific urban expansion, reasonable urban spatial layout, and sustainable urban economic development.

At present, the integration of urban and rural public transportation Hohhot is at an early stage, the thesis mainly studies the management of the integration of urban and rural public transportation system, analyzes the existing problems of integration of urban and rural public transport management system, puts forward the major traffic management mode, in the presence of Hohhot itself, puts forward about the strategy for the development of the integration of urban and rural public transportation management system, through these proposals and Suggestions to promote the development of Hohhot urban and rural public transportation integration.

Firstly, this paper gives the concept and characteristics of urban agglomeration, and analyzes the relationship between urban transport systems and urban transport group between. Then in urban agglomerations disequilibrium between supply and demand characteristics of the traffic, and analyzes the factors that influence urban agglomeration traffic. And expanding the range of travel modes, including road, rail, air and maritime transport, proposed determination method of urban agglomeration traffic supply and demand disequilibrium. Finally, numerical example is used to analyze its practicality and feasibility.

Based on the impact analysis of common rail transportation on urban rail transit and comprehensive consideration of Hohhot, including passenger flow characteristic analysis and related product design principle, this paper studies the impact of common rail transport system on the urban rail transit and describes the product design of common rail transport system of Hohhot in two aspects: common rail train stop plan and the nature of the passenger flow, which is dedicated to provide relevant theoretical basis for the rail transit planning and construction of Hohhot in the future. Key words: the integration of urban rail transit; common rail transport; product design; Hohhot