Asymmetric cycloaddition reactions represent a powerful strategy for building up complex molecular architectures, especially those with medium-sized rings. Herein, we disclose a highly diastereo- and enantioselective cycloaddition strategy that involves...

Enantioselective higher-order cycloaddition involving gold-furyl 1,3-dipoles is an attractive but challenging transformation for the construction of chiral polycyclic medium-sized rings from readily available building blocks. Here, the gold-catalyzed asymmetric [4+3]...