Endometrioid carcinoma is the most common histological type of concurrent synchronous cancers of the uterus and ovary. Here we report a case of synchronous seromucinous carcinoma of the ovary and mucinous carcinoma of the endometrium with a literature review. A 51-year-old multiparous female complained of irregular bleeding and shortness of breath. Computed tomography revealed a large pelvic mass that consisted of cystic and solid components, a tumor of the endometrium, and a large amount of pleural effusion. An endometrial biopsy indicated adenocarcinoma, and adenocarcinoma cells were found in the pleural fluid. The patient with advanced ovarian cancer or endometrial cancer with massive pleural effusion received three courses of neoadjuvant chemotherapy (NAC) with paclitaxel and carboplatin followed by interval debulking surgery (IDS). The NAC was effective, and IDS was performed with no gross residual lesions. The post-operative diagnosis was seromucinous carcinoma of the ovary in FIGO (2014) stage IVA (ypT3cNxM1a) and mucinous carcinoma of the endometrium in FIGO (2008) stage IA (ypT1aNXM0). Three courses of postoperative TC therapy were performed, and maintenance therapy with Bevacizumab is ongoing. The patient is well without evidence of recurrence, sixteen months after surgery.

Proteinuria during pregnancy is often associated with preeclampsia (PE) but may also indicate aggravated or newonset renal disease. As recently reviewed by Bartal et al., 1 2% of pregnancies exhibit isolated gestational proteinuria, and progress to PE or severe PE at a rate of up to 30%. As isolated proteinuria is part of the multisystem disease of PE, it shares many risk factors with PE. 2 In particular, patients with late-onset isolated proteinuria, at 33-36 or 37 weeks and later, were found to be at an elevated risk for PE, equal to 2.44 (95% CI: 0.80-4.08)-or 8.62 (95% CI: 7.54-9.70)-fold, respectively. In the clinic, however, proteinuria in the absence of gestational hypertension often does not flag a pregnancy as high risk or commit it to robust monitoring protocols.Ascites is sometimes observed in PE patients. Previously, it was reported that 1.9 of 1000 PE cases exhibit ascites. This rate increases to 21.6 of 1000 patients if the PE has severe features. 3 Ascites associates with poor outcomes for both mother and neonate, but the evidence is limited. 4,5 In addition to severe PE, ascites arises from independent underlying conditions such as portal hypertension, inflammatory diseases, malignancies, and diseases associated with low hypoalbuminemia. Here, we report a patient with massive ascites becoming prominent postpartum associated with late-onset preeclampsia. | CASE REPORTOur patient was a 26-year-old primigravid woman managed by an obstetrics practitioner at a private clinic over the course of a naturally conceived pregnancy. She had no history of hypertension or kidney disease, but proteinuria (3+ by urine dipstick test) was observed after 35 weeks'

Preeclampsia causes various presentations by increased endothelial permeability and microvascular damages. Maternal ascites related severe preeclampsia is generally explained by increased capillary permeability due to endothelial cell dysfunction and reduced intravascular oncotic pressure. Here we report a patient with postpartum massive ascites associated with preeclampsia.

No abstract