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The compound 4-hydroxy-3-methoxycinnamic acid, named as ferulic acid (FA), is a ubiquitous phenolic compound which is distributed extensively in the plant kingdom. Ferulic acid is a boon as it shows immense potential therapeutic effects which are useful in the treatment of diabetes, cancer, pulmonary and CVS diseases majorly due to its anti-oxidant and anti-inflammatory action. Ferulic acid exhibits other wide variety of biological activities such as, anticarcinogenic, antiallergic, antimicrobial, antiviral, hepatoprotective, metal chelation, activation of transcriptional factors, modulation of enzyme activity, gene expression as well as signal transduction. The structural characteristics of this active ingredient make it an optimal substrate to form or synthesize various derivates and its formulations. The present review addresses structure of ferulic acid, its pharmacodynamic parameters, applications and its various derivatives. In addition, the review also aims to cover the main aspects related to use of ferulic acid in the food and health industry and have listed various published patents on Ferulic acid.

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Owing to the enhanced toxicity as well as consequences of allopathic medication, the research on herbal therapies is developing progressively. As a result, medicinal herbs are beginning to play a substantial role in the advancement of the dominant therapeutic medications. Since ancient times, the use of herbs has performed a vital part in human well-being as well in the invention of cutting-edge pharmaceuticals. Inflammation and related illnesses are a major health concern for the entire human population. Pain-inducing drugs including opiates, non-steroidal anti-inflammatory drugs, glucocorticoids, and corticosteroids have severe side effects and these therapies suffer from the recurrence of symptoms too after discontinuing the treatment. As a result, the diagnosis along with the advancement of medications with anti-inflammatory properties is the priority to conquer the drawbacks of the existing therapies. The present review article provides insight into the literature comprising promising phytochemicals from various medicinal plants tested through different model systems and employed for alleviating inflammation in several inflammatory disorders as well as clinical status of the herbal products.