BACKGROUND: Today, minimally invasive coronary surgery is not only a good alternative to classical sternotomy, but also represents a separate developing area of cardiac surgery with the development of more and more low-traumatic techniques, such as minimally invasive direct coronary artery bypass and minimally invasive direct coronary artery bypass (MICSCAB). CLINICAL CASE DESCRIPTION: The advantages and disadvantages of these techniques are widely discussed in modern literature, and their practical application is ambiguous. This article describes a clinical case of successful coronary artery bypass grafting using the MICSCAB technique in a patient with a long history of coronary artery disease and a complex multivessel lesion. CONCLUSION: The presented clinical case proves the advantage of MICSCAB technique in comparison with traditional coronary bypass surgery.