Bio-organic agriculture considers the medium- and long-term impact of agricultural interferences on the agro-ecosystem. It aims to produce food while setting an ecological balance to soil fertility. Bio-organic agriculture takes a proactive design as opposed to treating problems after they emerge, so the study was conducted for studying two factors: First: the cultivars (Riviera and Arizona) class A resulting from cultivation of class E imported and cultivated in spring season 2018. The second factor: fertilizer combinations (bio-organic fertilizers compared with traditional chemical fertilizers). Arizona cultivar significantly achieved the highest values, in most of the study parameters compared to Rivera cultivar. Significant differences were observed between the treatments of fertilizer combinations, the treatment (organic fertilizer + bio-fertilizer + 25% chemical fertilizer) significantly achieved the best values compared to the control. Bi-interaction treatment (Arizona cultivar + organic fertilizer + bio-fertilizer + chemical fertilizer 25%) achieved the highest yield per hectare (43.24 tons.ha−1).