Amylose tris(3,5-dimethylphenylcarbamate) (ADMPC) and tris(3,5-dichlorophenylcarbamate) (ADCPC) were supported on macroporous silica gel to use as chiral stationary phases for HPLC. ADMPC showed higher optical resolving power for some enantiomeric pairs than cellulose tris(3,5-dimethylphenylcarbamate), and gave a practically useful chiral HPLC column. ADCPC resolved a few racemic drugs efficiently.
A variety of racemic carboxylic acids have been for the first time directly resolved by normal-phase, high-performance liquid chromatography using a hexane-2-propanol eluting system containing a small amount (≈1%) of a strong carboxylic acid, like formic acid, trichloroacetic acid, and trifluoroacetic acid.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.