Abstract-The effects of crude and processed ginger extracts and pungent com ponents, S-(+)-[6]-gingerol and [6]-shogaol, on noradrenaline (NA) and pros taglandin (PG) F2a-induced contraction were investigated using mouse mesenteric veins. Both spicy constituents inhibited the contractile responses to NA. Crude ginger extract and S-(+)-[6]-gingerol potentiated the PGF2a-induced contraction, whereas processed ginger extract and [6]-shogaol inhibited the contraction.
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