An investigation of the Ammon's horn seizure with macro-electrodes has been conducted in our department by Harafuji6) and Oka7>. But in the experiments using macro-electrodes, there is a limit to the analysis of wave pattern and it is impossible to isolate neuronal elements which participate in the development of seizure. Therefore, the present study was designed to use micro-electrodes in order to investigate the activity of neuronal elements at the time of seizure and thus to make clear the arising mechanism of the seizure discharge').
Summary
With a rather small number of cases treated with the Lente‐insulin, it would be risky to draw a conclusion on the therapeutic effect of this preparation. However. during the above‐mentioned tests, the favorable results were observed in some of the patients with chronic schizophrenia who did not respond to the regular insulin‐, and electroshock therapy, not saying of resistent cases to regular, insulin. And in one case (Case 7), Lente‐insulin exhibited a remarkable effect on a patient who had the initial attack of the disease.
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