This paper describes the effect of molten salt reduction on exothermic characteristics of Ti/reduced-SiO2 nanoparticles. Sputtered Ti/Si multilayer film is known to show exothermic reaction by electrical shock or mechanical impact during intermetallic compound formation. So far, we demonstrated that SiO2/Ti nanoparticles, which are produced by combining atomized heating for porous SiO2 nanoparticle and sputtering for Ti deposition, show exothermic reaction. if an amount of oxygen in SiO2 nanoparticles can be changed, it is expected that exothermic characteristics can be controlled more accurately. In this paper, the effect of reduction on exothermic reaction is investigated, and the mechanism of the reduced effect is discussed based on the result of differential scanning calorimetry analysis.