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Objectives Patients awaiting kidney/pancreas transplants are affected by end-stage renal disease (ESRD) or by severe insulindependent mellitus diabetes (IDMD), that have progressively lead to severe renal insufficiency. With the progression of those chronic illnesses, patients are susceptible to experiencing symptoms that affect their daily lives. Anxiety and depression may be induced by somatic condition and awaiting transplantation, contributing to the perception of quality of life (QOL). Aim of the study is to assess quality of life, lifetime and current DSM-IV Axis-I and II disorders, and finally sub-threshold mood and panic-agoraphobic phenomenology in a large sample of ESRD and IDMD patients awaiting kidney-pancreas transplants. Methods 227 consecutive transplant candidates of both genders, aged between 18 and 65 years. Axis-I and II diagnoses were performed using SCID-I and II. Patients were also administered the MOODS-SR and the PAS-SR to assess mood and panic-agoraphobic spectrum and the Q-LES-Q to assess quality of life, enjoyment and satisfaction. Results The prevalence of current Axis-I disorders was 13.2%. The most common current axis-I disorders were Agoraphobia (4.8%) and Major Depressive Episode (4.0%) No difference was found in the diagnostic distribution between the two groups. Quality of life among overall sample was poorer than that of a healthy adult population. Conclusions Our findings underlined the importance of careful evaluation of depressive symptoms during the pre-transplant and post-transplant course that include a sub-syndromal symptoms assessment. A systematic screening for depressive symptoms by means of self-report spectrum instruments, during the pre and posttransplant course, is valuable. AIM:To retrospectively analyse the mortality at one year in our renal transplant programme. MATERIALS AND METHODS: Patients who underwent renal transplant in our unit were analysed retrospectively. The mortality in the first year post renal transplantation in relation to the timing and the cause of the patient death were analysed. RESULTS: This study period was from August 1999 to Feb 2010. Total no of patients were 187 of which male: female 156: 31. The basic renal disease were Diabetic nephropathy: 24, Hypertensive nephroselerosis: 16, Chronic glomerulonephritis: 62, Chronic pyelo nephritis / Interstitial nephritis: 51, others: 34. Age group of the recipient (in years) < 20 -02 , 20 -30 : 22 , 30 -40 : 60 , 40 -50 : 54 , 50 -60 : 44, > 60 : 05. 126 (67 %) patients received Cyclosporine + Azathioprine + Prednisone based on immunosuppressions and 61 (33%) patients received Cyclosporine + MMF + Prednisone based on immunosuppressions.During the study period 15 (7.5 %) patients died in the 1 st year of post transplantation 7 patients died due to graft loss and were unable to afford for haemodialysis and second Transplantation. There were 3 deaths related to hepatitis -C related liver failure, 2 patients died due to sepsis, 1 patient died due to acute myocardial infraction and 1 patient died follow...

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