These in vitro studies suggest that ACS is able to increase matrix component production by human chondrocytes and to inhibit the negative effects of IL-1 beta.
The hamster flank organ model was used to measure the effects of clofibric acid on the in vitro uptake of sodium [1-14C] acetate into lipids. Clofibric acid produces a dose-dependent inhibition of lipogenesis in the hamster flank organ in vitro.
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