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This article contains results of joint works by Konstruktorskoe Buro Khimavtomatiki (KBKhA, Russia) and AVIO Company (Italy) on creation of the LM10-MIRA liquid-propellant rocket demonstrator engine for the third stage of the upgraded “Vega” launcher. Scientific and research activities conducted by KBKhA and AVIO in 2007–2014 in the frame of the LYRA Program, funded by the Italian Space Agency, with ELV as Prime contractor, and under dedicated ASI-Roscosmos interagencies agreement, were aimed at development and testing of a 7.5-ton thrust expander cycle demonstrator engine propelled by oxygen and liquid natural gas (LNG).