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RESUMEN -La meningoencefalitis amebiana primaria (MAP) es infrecuente. Describimos dos nuevos casos de MAP en pacientes Venezolanos. Caso 1, Varón de 10 años, con fiebre, cefalea, vómitos y debilidad generalizada, y antecedente de inmersión en un estanque de agua días antes del inicio de sus síntomas, falleciendo 72 horas después del ingreso. Caso 2, Varón de 23 años con historia de cefalea, fiebre, vómitos, somnolencia y cambios de conducta. El paciente falleció 40 horas después. El estudio neuropatológico en ambos casos reveló MAP por Naegleria fowleri. La encefalitis por amebas anfizoicas debe sospecharse en casos de meningoencefalitis asépticas.PALABRAS CLAVE: amebas de vida libre, meningoencefalitis amebiana primaria, Naegleria fowleri. Primary amebic meningoencephalitis: two new cases report from VenezuelaABSTRACT -Primary amebic menigoencephalitis (PAM) is rare. Two cases of PAM in Venezuelan patients a re described. Case 1, a 10 year-old male with headache, fever, vomiting. The patient swam in a water reservoir before the onset of his disease. He died during his third hospital day. Case 2, a 23 year-old male with a history of headache, fever, vomiting, drowsiness, and behavioral disturbances. The patient died on his second hospital day. The diagnosis in both cases was PAM due to Naegleria fowleri. Central nerv o u s system infection by free-living amebas should be considered in meningoencephalitides with bacterial-fre e cerebro-spinal fluid.

A case of fatal balantidial infection with appendicular and pulmonary involvement in a Venezuelan farmer is reported. The clinical, post-mortem and histological features are described.

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Penile cancer is uncommon in western countries. It has been related to human papilloma virus (HPV) types 16 and 18. We describe five cases of carcinoma of the penis in men from a rural Venezuelan town that were related to HPV types 6, 11, 53, which represent a rather low risk for cancer.