Tailing waste from gold mining in Papua, Indonesia, is a severe problem for the environment. Tailing as Hazardous and Toxic Substances, the deposits so massive. On the other hand, the availability of natural aggregates for road pavement continues to run low. The problems can be solved by utilizing tailing as a road base layer with massively, fulfill specification, and save. The purpose of this research is how to utilize tailing as a road base layer. The research methods used are experiment laboratory method by physical, chemical, TCLP, and mechanical strength test. The physical analysis shows that the size of the tailing is loose and non-cohesive, so it requires binding material to increase bearing capacity. The TCLP test showed that the level of toxic material in tailing was fulfilled the threshold. The stabilization analysis of tailing with 20% clay soil produces CBR 17,3% and can only be utilized as embankment. Stabilization with 13,35% cement fulfills the target UCS 24 kg/cm2 to be used as a road base layer. Marshall test result by 60% tailing and 7% asphalt meet specifications to be asphalt road base layer.