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To assess the nature of the clinical evolution of chronic gastritis, we observed 40 patients suffering from various forms of this disease for a long time (from 1 to 7 years). Among them there were 6 women and 12 men under the age of 40, 9 women and 13 men over 40. 7 patients suffered from chronic gastritis with preserved gastric secretory function, 11 patients suffered from chronic gastritis with reduced secretory function, 17 had no free HC1 in the gastric contents, and 5 patients (also with an anacid state) had gastritis of the operated stomach (Billroth II resection for ulcerative disease). In 33 patients, chronic gastritis was the main disease, in 7 it was combined with chronic inflammation of the biliary tract. At the beginning of the follow-up, 11 patients with chronic gastritis were accompanied by lesions of the biliary tract and in 2 - intestinal inflammation. In 5 patients, the duration of the disease with chronic gastritis was up to 1 year, in 7 - up to 3 years, in 4 - up to 5 years, in 12 - up to 10 years and in 12 - more than 10 years. During the year we observed 11 patients, 2 years - 11, 3 years - 3, 4 years - 5, 5 years - 7, 6 years - 2 and 7 years - 1. At the beginning and end of the observation period, the patients were examined and treated in a hospital, the rest of the time - in a polyclinic, some of the patients were hospitalized 3-4 times.

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In spite of the established ideas about peptic ulcer as a general disease of the whole organism, there is a continuous flow of publications in which local treatment of ulcers of the mucous membrane of the stomach and duodenum is recommended. With the development of fiber optics, it became possible to target the ulcers, activating reparation processes in them. Adhesives and film-forming compositions MK-6, Lifusol, Gastrovol etc. were used to cover the ulcers.