Синдром сухого глаза (ССГ) является многофакторным заболеванием, которое вызывает дискомфорт, зрительные нарушения и сопровождается уменьшением слезопродукции, нестабильностью слезной пленки, увеличением скорости испарения и осмолярности слезы, что потенциально обусловливает воспалительный процесс поверхностных структур глаза [1-4]. Лазерная кераторефракционная хирургия является одной из триггерных причин клинической манифестации уже имеющегося ССГ, нередко возникающего на фоне длительного ношения контактных линз у пациентов с аномалиями рефракции [5-10].

Purpose To investigate CCT and IOP in myopic adult Chinese and to estimate its relationship with age, refraction, sex before excimer surgery in Eye Department of Daqing People’s Hospital (the 5‐th Affiliated Hospital of Harbin Medical University). Methods We studied a series of 402 healthy eyes of 201 patients (76 male /37.8%/, 125 female /62.2%/) who underwent excimer surgery for the correction of myopia with the sphere up to ‐13.5.0 D and the cylinder to ‐4.50 D. All ophthalmic investigations were made including pneumotonometry (“”Canon” TX‐10 and T‐F) and ultrasound (US‐) corneal pakhymetry with CCT‐measurements (“Nidek” UP‐1000). We performed accurate statistical analysis by using “Statistica” program. Results The age of our patients was 26.5+/‐6.3 years. UCVA and BCVA of all patients were 0.13+/‐0.09 and 0.97+/‐0.09 consequently. The results showed that mean US‐CCT of our male patients was 548.03+/‐29.12 microns. But mean CCT of our female patients was 537.77+/‐32.09 microns, 10.26 microns less than that of male patients (p<0.01). The mean IOP of male participants was 16.23+/‐2.94 mm Hg, and mean IOP of female participants was 14.82+/‐2.74 mm Hg (p<0.01). Conclusion Our results confirmed some data (P. Li et al., 2006) that mean US‐CCT of male patients was statistically significant more than such measurements in female ones in myopic adult Chinese. We revealed that pneumotonometric IOP was positively related to US‐CCT (r>0.85). None of the authors has no financial interest in this work.

Purpose To estimate the visual and refractive outcomes of simultaneous bilateral PRK (FAREK) for the correction of difficult cases of high myopia with steepest and very thin cornea in Chinese patients. Methods We studied a series of 38 eyes of 19 patients who underwent simultaneous bilateral PRK (FAREK) for the correction of myopia with the sphere up to ‐15.6 D and the cylinder to ‐2.75 D in difficult cases with the steepest and very thin cornea. Coefficient K2 was up to 49,0D and central corneal thickness was 504.3+/‐33.5 microns. Simultaneous bilateral PRK by using Mytomicin C, soft contact lenses, cooling effects was performed by Russian surgeons with the NIDEK EC‐5000. Follow‐up period was up to 3 months. The age of our patients was 25.2+/‐5.3 years. Pre‐op UCVA and BCVA were 0.12+/‐0.10 and 0.94+/‐0.14 consequently. Results Day of epithelization was 3.3+/‐0.8. Post‐op UCVA was 0.48+/‐0.18 in the epithelization’ day, 0.63+/‐0.21 in the first week, 0.79+/‐0.25 in the first month and 0.89+/‐0.25 in the third month after FAREK. Pre‐op IOP was 13.9+/‐2.9 mm Hg. Post‐op IOP was 8.2+/‐1.8 in the epithelization’ day, 7.8+/‐1.6 in the first week, 9.7+/‐2.2 in the first month and 10.0+/‐2.3 in the third month. UCVA was equal or more than 1.0 in 2.6% in the epithelization’ day, 13.8% in the first week and 41.6% in the first month after FAREK. There were no serious complications including hypertensions in all cases. Conclusion We called our method FAREK – fast recovery excimer keratectomy. FAREK is a safe, reliable and effective method for the correction of difficult cases of high myopia with steepest and very thin cornea in Chinese patients. None of the authors has no financial interest in this work.

Purpose To investigate the results of LASIK surgery for myopia in Chinese patients in Joint Russian‐Chinese Ophthalmic Center. Methods We reviewed our consecutive 296 cases (148 chinese patients, including 92 women and 56 men) of LASIK surgery for myopia with the sphere from ‐1.0 to ‐13.5 D and the cylinder till ‐4.5 D. LASIK was performed by Russian surgeons with the NIDEK EC‐5000 excimer laser and microkeratomes LSK Evolution‐2 (“Moria”). Follow‐up period was up to 3 months. The age of our patients was 26.7+/‐6.2 years. Pre‐op UCVA and BCVA were 0.13+/‐0.08 and 0.97+/‐0.08 consequently. All patients had standard ophthalmic examinations, including pneumotonometry, refractometry etc. We performed statistical analysis by using "Statistica" programm. Results Ablation depth was 89.3+/‐24.5 microns, ablation time was 47.53+/‐15.26 sec. Post‐op UCVA was 0.85+/‐0.24 in the first day, 0.97+/‐0.23 in the first week, 1.05+/‐0.20 in the first month and 1.10+/‐0.11 in the third month after LASIK. Pre‐op IOP was 15.6+/‐2.9 mm Hg. Post‐op IOP was 10.2+/‐2.7 in the first day, 10.5+/‐2.5 in the first week, 10.7+/‐2.9 in the first month and 9.1+/‐2.6 in the third month. UCVA was equal or more than 1.0 in 51.0% in the first day, 71.1% in the first week and 79.1% in the first month after LASIK. There were no serious complications in all cases. Conclusion The results of LASIK surgery for myopia in Chinese patients in the Joint Russian‐Chinese Ophthalmic Center were effective and successful. LASIK surgery by using NIDEK EC‐5000 excimer laser gives predictable and good results in Chinese patients. None of the authors has no financial interest in this work.