Level IV: prospective non-randomized, non-comparative observational study.

Key Clinical MessageIn the presence of megacystis in the second half of pregnancy, with increased amniotic fluid, especially in a female fetus, the most likely diagnostic result is megacystis, microcolon, intestinal hypoperistalsis syndrome, MMIHS. In these cases, the diagnosis of MMIHS should be strongly considered instead of lower urinary tract obstruction.

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The 3D Printing technology is a relatively modern technology, which since its appearance in 1983, had an important and constant development. In the past decade 3D printing became more and more integrated in different areas of expertise, particularly due to an increasing level of accessibility by decreasing the prices of 3d printing machines and also due to the expansion of what used to be a niche market for 3d printing materials. Thus, 3D printing quickly became a powerful tool for areas such as medicine, automotive, airspace industry, product design, weapons industry, etc. This article approaches the role and evolution of 3D printing in medicine and how this technology is set to revolutionize medical practice by pushing it further and further, in order to reach the ideal personalized, predictive and increase safety medical treatment.