Kobalticinium‐hexafluorphosphat (I) geht beim Behandeln mit Natriumhydroxid oder Natriumamid über die diskutierten Zwischenstufen (II) und (III) in Azulen (IV) über.

1996 amide formation, amide hydrolysis amide formation, amide hydrolysis O 0320 -102Ritter Reaction of Cyclic Hydroxyamines:Synthesis of Conformationally-Restricted Reduced Amide Dipeptide Isosteres.-It is found that the Ritter reaction of the pyrrolidine (I) and the piperidine (VI) proceeds smoothly giving the desired products (III) and (VII) in good yields. On the other hand, starting from the azetidine (VIII) and the piperidine (X) only low yields are obtained. Desired 3-acylamino-3-alkylpiperidines like (XV) can be prepared effectively via Hofmann rearrangement of corresponding amides. The pyrrolidine (III) and the piperidine (XV) are transformed into the dipeptide isosteres (V) and (XVI) in order to test their use as enzyme inhibitors.-(TAYLOR, G. M.; BAKER, S. J.; GEDNEY, A.; PEARSON, D.

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Aus einigen durch gleichzeitige Addition von Brom und Chlor an Benzol erhaltenen Reaktionsprodukten konnten die folgenden Hexaheterohalocyclohexane der 1.2.3.4.5.6-Reihe abgetrennt werden: C6H6Cl4Br., (I) Die Zahl der theoretisch möglichen Sessel-Konfigurationen der Dibromtetrachlor-und Tetrabromdidilorcyclohexane der 1.2.3.4.5.6-Reihe ist beträchtlich: Vom 1.2-Dibrom-3.4.5.6-tetrachlor-cyclohexan lassen sich 72, 3 G. E ni s c h w i 11 e r u. J. L. S a c o n n e v . Bull. Soc. chim. France, Mem. (5)

C 12 H 22 CdN4O14, triclinic, P¯ (no. 2), a = 7.188(2) Å, b = 8.895(3) Å, c = 9.771(3) Å, α = 63.148(3)°, β = 76.750(3)°, γ = 66.225(3)°, V = 509.2(3) Å 3 , Z = 1, Rgt(F) = 0.0253, wR ref (F 2 ) = 0.0676, T = 296(2) K. CCDC no.: 1484775The crystal structure is shown in the gure. Tables 1 and 2 contain details of the measurement method and a list of the atoms including atomic coordinates and displacement parameters. Source of materialThe title compound was synthesized by a hydrothermal method under autogenous pressure. A mixture of CdCl 2 ·H 2 O