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Abstract:Flavonoids are a group of common natural occurring polyphenolic compounds that are widely found in the plant kingdom. They occur naturally as plant pigments in a broad range of fruits and vegetables as well as beverages such as tea, red wine, coffee and beer . Many of the known 4000 different flavonoids to date are part of our regular diet . Flavonoids can be subdivided into several classes such as dihydrochalcone, chalcone, flavanones, isoflavones, aurones and flavone. The skeleton of a large class of flavonoids is known as flavone. Flavonoids have attracted the interest of researches because they showed promise of being powerful antioxidants which can protect the human body from free radicals. The interest in the biological properties of flavones has resulted intense synthetic efforts towards the synthesis of various flavones derivatives with the help of mannich reaction.