This work was carried out in four selected provinces in Beni-Suef Governorate, Egypt to investigate the possibility of existence of different types of enteric parasites infect 2-5 years old sheep and estimate the rate of improvement in some of its productive parameters post eradication of these parasites in relation to each parasitic infection. The study cleared that gasterointestinal bursated nematodes (Haemonchus spp., Trichostrongylus spp., Ostertagia spp., Nematodirus spp. and Cooperia spp.) and Fasciola are the most common parasites infecting sheep (57.44% & 48.44% respectively), this was followed by Paramphistopmum infection (38.88%), Moniezia spp. (33.11%), different types of Eimeria spp. (29%) and finally Trichuris spp (7%). Fecal culture of positive samples demonstrate presence of five types of nematode larvae include Haemonchus spp. larvae (33.75%), Oestertagia spp. (31.5%), Trichostrongylus (11.75%), Cooperia spp. (14.5%) and Nematodirus spp. (8.5%). Using of ivermectin for treatement of GIN, Nitroxynil for treatment of Fasciola, and oxyclozanide for treatment of Paramphistomum species infection, induce marked decrease in the mean number of different eggs per gram (e.p.g.) of faeces associated with improvement in mean body weight gain (5.71 Kg) and rate of lambing (26.77) after 6 months post treatment. High rate of improvement post treatment was recorded in animals originally free from Fasciolia infection, also and that harboring low e.p.g. than animals of high e.p.g. Finally it was evident that high rate of improvement was cleared in animals less than 4 years old in comparison by that over 4 years old.