Peutz-Jeghers syndrome is an autosomal dominant inherited disorder characterized by hamartomatous polyps in the small bowel and mucocutaneous pigmentation. Patients with Peutz-Jeghers syndrome often present as surgical emergencies with complications of the polyps, such as intussusception, bowel obstruction, and bleeding. Recently an increased risk of malignancies has also been reported. This study was initiated to determine the clinical features of Peutz-Jeghers syndrome in Korean patients, with special attention to the development of malignancies. Thirty patients with Peutz-Jeghers syndrome were investigated; their median age was 23.5 years, and symptoms appeared at a median age of 12.5 years. Family history was positive in one-half of cases, and mucocutaneous pigmentation was observed in almost all patients (93%). The jejunoileum was the most frequent site of the polyps, and there were generally 10-100 polyps. Multiple laparotomies were performed in a substantial portion of the patients, due mainly to polyp-induced bowel obstruction, and the surgical interventions were begun at a relatively young age (average 21.4 years). Four cases of small-bowel cancer and one case of breast cancer were detected in probands, at a relatively young age (mean 36 years). Cancers of the small bowel, stomach, colon, breast and cervix were diagnosed in the first relatives of the probands. Close follow-up from an early age should thus be performed in patients with Peutz-Jeghers syndrome as they are at high risk of surgical emergency and development of malignancy.

KEY WORDS: intussusception; sigmoid lipoma; mimicking carcinoma.Colonic lipomas are the most common nonepithelial tumor, and they are the third most common tumor, after hyperplastic and adenomatous polyps (1). The majority of colonic lipomas are small and asymptomatic (2). Large lesions may be significant because of their related symptoms, and especially, intussuscepted colonic lipomas are often confused with malignant tumors, so that most of them are diagnosed after intervention (3). We present a case of an intussuscepted lipoma mimicking a malignant tumor in a 62-year-old man. Intussuscepted colonic lipoma is uncommon, and a right-side intussuscepted colonic lipoma is especially rare. The malignant transformation of lipoma is extremely rare, and recurrent lipoma has never been reported. Nonetheless, operative or endoscopic intervention may be required to differentiate this lesion from a malignant or premalignant lesion. This case is very unique in the aspects of the lipoma's shape and size and the location in which it was found. CASE REPORTA 62-year-old man was admitted to the hospital because of left lower quadrant abdominal pain that had lasted for 1 month, with intermittent hematochezia. The patient said he did not have any fever or weight loss. Upon physical examination, he had pale conjunctiva, and there was left lower quadrant tenderness without rebound tenderness. There was also a relatively highpitched sound on abdominal examination. The rectal examination showed dark blood-tinged stool. The other findings from the physical examination were normal. The results of laboratory investigation, including the level of carcinoembrionic anti-