Lens opacity, which leads to cataract, is one of the most complicated issues in ophthalmology. Pathophysiology of cataract progression is far from being clearly established. Despite low lipid content in the lens of the eye, there is an assumption that they and their predecessors may be involved in the development of this disease. Given the many roles of monounsaturated fatty acids, it can be expected that variations in stearoyl-Coa desaturase activity will affect a number of key physiological processes.