Novel bis-andrographolide ether (1) and six known compounds andrographolide, 14-deoxy-11,12-didehydroandrographolide, andrograpanin, 14-deoxyandrographolide, (+/-)-5-hydroxy-7,8-dimethoxyflavanone, and 5-hydroxy-7,8-dimethoxyflavone have been isolated from the aerial parts of Andrographis paniculata and their structures were established by spectral data. All the isolates were tested for the anti-HIV and cytotoxic activity.

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Alkaloids U 0600New Potent Cytotoxic Lamellarin Alkaloids from Indian Ascidian Didemnum obscurum. -Among the alkaloids (I) and (II) isolated, derivatives (Ia) and (II) possess promising cytotoxic activity. -(REDDY, S. M.; SRINIVASULU, M.; SATYANARAYANA, N.; KONDAPI, A. K.; VENKATESWARLU*, Y.; Tetrahedron 61 (2005) 39, 9242-9247; Org. Chem. Div., Indian Inst. Chem. Technol., Hyderabad 500 007, India; Eng.) -Mischke 02-200

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