According to International Statistical Classification of Diseases -10, the following is defined: Q25.I Aortic coarctation (Aortic coarctation (preductal, postductul)).Frequency. The highest frequency of coarctation of the aorta is found with the infants (7,5-15% of all the congenital heart malformations) which is linked to the severe course of the defect among the patients of this age.Ethiology. The list of teratogenic factors, causing the malformation includes: alcohol, lithium, hydantoin, isotretinoin, thalidomide, rubella, mother's diabetes mellitus.

Hydronephrosis -a persistent progressive an abnormal dilation of the renal pelvis, and calices with disturbance of the urinary outflow, renal parenchymal atrophy and progressive decrease of its functions.According to ICD-10 congenital hydronephrosis is encrypted with Q 62.0. The term "hydronephrosis" was first introduced by P. Rayer in 1841.Frequency. Hydronephrosis is one of the most common diseases of the urinary system in children -2.8 deaths per 1,000 newborns, with 1.5 times more common in girls, unilateral.Etiology and pathogenesis.Is inherited in an autosomal dominant pattern.