Diabetic striatopathy is an uncommon neurological manifestation of hyperosmolar hyperglycemic syndrome. A case of a 74-year-old woman is presented here. She presented with abnormal movements of left upper and lower limbs and was found to have high index blood sugar. Non contrast CT brain showed hyperdense area in right striatal region. Based on clinical presentation, high blood sugar and radiological finding, she was diagnosed with diabetic striatopathy. The radiological abnormality and the symptoms improved rapidly and remarkably with strict glycaemic control.

Antiphospholipid syndrome (APS) is a thrombophilic condition leading to multiple complications. Primary APS rarely causes primary adrenal insufficiency, but it can be life-threatening. In the present report, a patient presents with symptoms and signs of adrenal insufficiency and subsequent hormone level tests and radiological findings led to a diagnosis of primary APS with adrenal insufficiency.

Posterior Reversible Encephalopathy Syndrome (PRES) is an acute encephalopathy characterized by headache, altered consciousness, visual symptoms and convulsions.Diagnosis is supported by Magnetic resonance imaging (MRI) of the Brain. Here we report a case of PRES in a 24-year-old-male who showed complete recovery with the control of blood pressure. Finally Post Infectious Glomerular Nephritis (PIGN) was found to be the underlying etiology of hypertension to develop PRES.