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It is essential that clinicians have a thorough understanding of the interplay between root canal microflora and the endodontic disease processes in order to develop an effective rationale for treatment. Newer information on endodontic micro flora improves our ability to effectively debride and disinfect the root canal system and manage infections of endodontic origin. New molecular based techniques have been introduced thus bringing about a massive change in procedures for microbial identification. This knowledge can be put into practical use resulting in improvements in the quality of treatment offered to our patients. This review focuses on the microflora in primary and root-filled canals of deciduous and permanent teeth.

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