The research work is focused on the development of bioactive composite wound dressings with desirable wound healing properties using needle punched nonwoven, chitosan, and manuka honey. Three different methods using film, half tone and dip & dry techniques, were devised to prepare chitosan-honey wound dressings with viscose and bamboo nonwoven as secondary layer and chitosan-manuka honey as primary layer. All the three dressings prepared have been evaluated for their effectiveness as wound dressing and characterized. The results indicate that the weight and thickness of almost all the samples are comparable. The film dressings showed a higher value of air permeability and water vapor transmission of 55 cm 3 /cm 2 /second and 1700 g/m 2 /day. The swelling ration of film dressings was 283%. Even though dip & dry dressings showed better antimicrobial activity and higher tensile strength, their elongation is low compared to film dressings. Half tone treated samples show poor coating in the morphological observation. Hence, from the obtained results, it can be concluded that the film wound dressings show considerable advantage over half tone and dip & dry dressings.

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The innovative technologies invented to produce fibres, yarns and fabrics have been paved way for the use of them in various fields other than clothing sector. Performance apparel represents one of the fastest growing sectors of the international textile and clothing industry. The medicines made from natural herbs are mostly not having any side effects as such in the case of chemically formulated drugs. The objective of this project is to develop curative textiles using natural herbs to heal the stage -I piles (Hemorrhoids), fistula and anal fissures in human being with the modern nanotechnology (i.e. microencapsulation Techniques). Microencapsulation is a technique where in tiny droplets/particles of liquid/gas/solid particles are applied to textile materials to achieve various effects. Garment gets unique property due to Micro encapsulation process. Micro capsules filled with Particles with active ingredients when applied to the fabric or garments give a functional finish with long lasting effects because the particles get penetrated to the fibre core. As the wearer moves, the capsules are activated producing a slow release of the active ingredient. In this research work an attempt has been made to articulate a controlled delivery of drug release which was extracted using natural herbs which inturn used to heal piles and fissure. For this purpose, the Core -substance prepared from the herbs are encapsulated in a Shell -Cyclodextrin or Alginate using microencapsulation technique. Cellulosic nonwoven fabric is treated with microencapsulated herb and dried. Then the colony of cultured Staphylococcus aureus & Escherichia coli bacteria is placed over the treated and untreated fabric under standard testing condition in a laboratory. After a week's study, the antibacterial activities were studied and systematically analysed.

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